Rv0340Rv0341: iniBRv0342: iniARv0343: iniCRv1267c: embRRv3124Rv3125cRv3126Rv3264c: rmlA2Rv3266c: rmlDRv3793: embCRv3794: embARv3795: embB


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Rv3126: all mutations (high confidence mutations are highlighted in yellow)
Primary reference Polymorphism Nucleotide position Codon position Amino acid Time period Origin Molecular detection method Gene coverage Resistance pattern MIC Susceptibility testing method R/Total isolates R/S isolates with mutation Additional mutations High confidence support
Ramaswamy SV AAC 2000 - - 276 Leu/Arg Published 2000 USA, Russia Sequencing Whole gene E 50ug/ml BACTEC 460, agar diffusion method 75/108 1/0 Asn396Asp in embC, Gly350Asp and Pro913Ser in embA and -12 G deletion in Rv0340. -

Disclaimer: These are all putative mutations found in drug resistant clinical TB isolates. No a priori decisions have been made as to whether these mutations are causally related to resistance or possible secondary mutations.

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